Product Details

Product Name ::OLTHA-R

Description ::

OLTHA-R

(Olanzepine)

·        Category : Antipsychotic.

·        Mode of action : OLTHA-R is a medication that is used to treat Schizophrenia and main episodes associated with bipolar disorder. OLTHA-R belongs to a drug class known as atypical antipsychotics. The exact mechanism of action OLTHA –R is not known. It may work by blocking receptors for several neurotransmitters (Chemicals that nerve use to communicate with each other) in the brain. It binds to alpha-I , dopamine, histamine H-1, muscarinic and serotonin type 2 receptor.

·        Effect on the pancreas : There has been isolated reports of pancreatitis associated with OLTHA-R

·        Extrapyramidal disorders : There have been isolated reports of tartive dryskinesia associated with OLTH-R treatment. However, the incidence of extraphyranidal effects is generally lower with atypical than classical antipsychotics.

·        Absorption : OLTHA-R is well absorbed  from the G. I. tract after oral doses but undergoes considerable first pass metabolism. Peak plasma concentrations are achieved about 5 to 8 hours after oral doses. OLTHA-R is about 93% bound to plasma proteins.

·        Indications: OLTHA-R is used for treating Schizophrenia and acute mixed or manic episodes associated with bipolar disorders. It also is used as maintenance therapy for bipolar disorder and treating agitation due to Schizophrenia or bipolar disorders. OLTHA-R also used in combination with Fluoxetine for treatment of resistant depression associated with bipolar disorder.

·        Dosage :

1.     Usual adult dose for Schizophrenia: oral—initial dose: 5 to 10 mg orally once a day. Maintenance dose: 10 mg orally once a day. Maximum dose: 20 mg orally once a day.

2.     Usual adult dose for bipolar disorders: oral—(monotherapy) --- initial dose: 10 to 15 mg orally once a day. Maintenance dose: 5 to 20 mg orally once a day. Maximum dose: 20 mg orally once a day.

3.     Usual geriatric dose for bipolar disorders: oral--- initial dose: 5 mg orally once a day of deliberated or predisposed to hypotension. Maintenance dose: may increase cautiously.

4.     Special caution : The following drugs can interact with OLTHA-R

·        A medication to treat high blood pressure

·        Carbamazepine

·        Flavoxamine or

·        A medication to treat Parkinson’s disease including levodopa & others

·        Liver disease

·        Kidney disease

·        High cholesterol or triglycerides

·        A history of heart attack or stroke

·        A history of breast cancer

·        Seizures or epilepsy

·        A personal or family history of diabetes.

 
     Side effects :

·        Fever, stiff muscle, sweating, fast or unheven heart beats, jerky muscle movement you cannot control. Sudden headache, confusion, problems with vision, speech or balance etc.

·        Presentation : OLTHA-R…Olanzapine Mouth Dissolving…2.5/5/7.5/10/15/20 mg Tab.

 

Few competitive preparations :

BRANDS

COMPANY

BRANDS

COMPANY

 

 

 

 

JOLYON-MD

LUPIN

MANZA

ORCHID(PSYCHIATRY)

OLACE

LA PHARMA

OLANEX

RANBAXY(SOLUS)

OLEANZ

SUN

OLEXAR

CIPLA(PROTEC)

OLIZA

INTAS

TOLAZ

TORRENT

 

 

 
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